Andriol is an oral testosterone steroid. Methyltestosterone is the other orally active testosterone. The steroid Andriol has a distinct absorption system. When taken with food it is assimilated through the mucosal cells in the small intestine. This steroid thereby avoids absorption through first pass deactivation in the liver. This equals a higher level of the Andriol steroid enters the blood. Some of the steroid is then converted into DHT (dihydrotestosterone) which has a high atraction to androgen receptors. Andriol does not convert into estrogen at a high level like other testosterones. This is also why water retention is lower, as well as gyno and female pattern fat deposits are far less common. Andriol has a reputation for a low negative effect on the HTPA (hypothalamic pituitary testes axis) and is not know to suppress natural androgen production to a great degree with the lower reported dosages. This is mainly due to estrogen’s negative effect that HPTA function is decreased. However, estrogen has to be present in low levels for steroids to reach there full effectiveness.